Computational Neurology and Psychiatry Peter Erdi, Basabdatta Sen Bhattacharya and Amy L. Cochran (Editors)
Anxiety: A common effect of various types of drugs that reduce behaviors characteristic of anxiety is the reduced frequency of a slow oscillatory activity called hippocampal theta rhythm. The frequency of hippocampal theta rhythm increases linearly with the intensity of electrical stimulation to a region of the brainstem. The reduction of mean frequency and the slope of this linear relationship between stimulation intensity and theta frequency predicts the clinical efficacy of anxiolytic drugs. Combined physiological - computational studies help to uncover neural mechanisms. The purpose of this research was to investigate the mechanisms by which anxiolytics produce this characteristic effect on the slope and intercept of the stimulus-frequency relationship of hippocampal theta.
Schizophrenia: is a complex disease of very diverse symptoms and mostly unknown causes. A possible underlying phenomenon is described by the "disconnection syndrome" hypothesis, when the control signal flow between cortical areas is impaired. We examine dthe differences in the causal connection patterns and strengths between healthy and schizophrenic subjects.
Prediction of technological development Vision: Identification of branches of technologies based on patent citation data Identification of patterns how these branches develop, such as rapid growth, shrinking, split and merges Identification of governing rules that are able to explain the pattern (backtesting) Come up with predictions for the near future: Which are the technologies of tomorrow?
Péter Érdi and Gábor Lente:Stochastic Chemical Kinetics. Theory and (Mostly) Systems Biological Applications (Springer Series in Synergetics) . Springer, 2014 |
Péter Érdi: Complexity Explained. Springer, 2007 |
Péter Érdi and János Tóth: Mathematical Models of Chemical Reactions: Theory and Applications of Deterministic and Stochastic Models. Princeton University Press | |
Michael A Arbib, Péter Érdi and János Szentágothai: Neural Organization: Structure, Function, and Dynamics. The MIT Press |