Welcome to the Wilson Research Group
Projects - Aug 2021
Three areas of our research into spherical viruses include
1. Understanding the maturation of virusese
2. How to modify viral capsids for nano-medicines.
3. Interior modifications of viral capsid for drug encapsulation
Past Meetings<\b>
West Michigan Undergraduate Research Meetings
FASEB
5th Gordon Research Conference on Physical Virology in Ventura, CA. Organized by amazing Tuli Mukhopadhyay and Wouter Roos! January 2019
Projects - Updates coming Fall 2021
Computing
Publications
Protruding Features of Viral Capsids Are Clustered on Icosahedral Great Circles
Protuding Features at PLOS1
Here we show that all spherical viruses use a common set of 21 sites within the Asymmetric Unit, which could have major implications on virus design and evolution.
David Wilson
Me
Biophysicist, father.
Email me dwilson@kzoo.edu
Tweet me @DrDaveWilson
Research Group! 2018/2019
Fomer Students:
Archie Bhullar
Senior Physics and Math, Now a PhD Student at OSU
Working on Maturation of HK97
Skylar Rizzolo
Senior Physics and Computer Science
Normal modes of viral capsids
Gil Gonzalez
Senior Chemistry and Biology, now a PhD Student at Purdue
Modifications to CPMV
Danielle Roof
Biology
Viral Phrenology, Now a masters student at Tulane
Current and Past Students
Student Year Year/Title
Rob Hammond , 2016 “The Mechanical Properties of Spherical Viral Capsids”, Student Awarded Grant Funding
Archie Bhullar , 2018 “6-D Lattice Phase Transformations in Viral Maturation”, Student Awarded Grant Funding
Skylar Rizzolo , 2018 “Exploring Viral Maturation Pathways Using Normal Mode Flexible Fitting Software”, Student Awarded Grant Funding
Adam Decker , 2019 “Understanding Normal Modes of HK-97” Sophomore Project, Student Awarded Grant Funding
Austin Cramer , 2019 “Examining the nonequivalence of affine extended point arrays and point sets from crystallographic projection”, Student Awarded Grant Funding
Evan Voyles , 2019 “Decomposition of Virus Normal Modes into Spherical Harmonics”. Awarded Honors in Physics (Evan was a Chemistry and Math major)
Matt Turton , 2019 “Utilizing Point Arrays to Further Classify Spherical Viruses Exhibiting Icosahedral Symmetry”, Student Awarded Grant Funding
Adam Decker , 2020 “Compactness of Icosahedral Viruses Reveals High Mass Packing of Protruding Features.” Awarded Honors in Physics, Student Awarded Grant Funding
Allison Frey , 2020 “Using Point Arrays to Further Analyze the Human Adenovirus Penton Base and Fiber Interaction in an Oncolytic Context”
Brandon Wright , 2020 “Localizing Epitope Locations Within Icosahedral Point Array Asymmetric Units and Capsid Depth for Canine Parvovirus and Human Rhinovirus-14”
Danielle Janowicz , 2020 “Characterizing Viral Protein Capsid Structural Changes Due to Maturation Using Icosahedral Point Arrays”, Student Awarded Grant Funding
Danielle Roof , 2020 “Comprehensive Analysis of the Relationship Between Triangulation Number, Baltimore Classification, Hosts, Point Arrays, and Gauge Points of Each Type of Spherical Virus”, Student Awarded Grant Funding
Blue Truong , 2021 “What Spherical Harmonics Don’t Tell You About Viral Normal Modes.” Sophomore Project, Student Awarded Grant Funding
Brianna Flinkinshelt , 2021 “Quantifying the key structural amino acid differences in the T3 Leviviridae phage family”, Student Awarded Grant Funding
Lily Rogowski , 2021 “Examining Structural Changes of HBV due to multiple drug bindings using Point Arrays.”, Student Awarded Grant Funding
Zachary Worthing , 2021 “Understanding Rhinovirus Antibody binding and structurally induced confirmations using Point Arrays.”, Student Awarded Grant Funding
Antelma Acosta , Spent 1 term in lab
Rachel Gallop , Spent 2 terms in lab.
Kayla Park , Spent 3 terms in lab
Aiden Hurley , Spent 4 terms in lab
Gil Gonzales , Spent 4 terms in lab
Hannah Shiner , Spent 4 terms in lab
Julia Dobrey , Spent 4 terms in lab
Lily York , Spent 4 terms in lab
Claire Kvande , Spent 1 term in lab, plans to continue Fall 2021
Mallory Dolorfino , Spent 1 term in lab, plans to continue Fall 2021
Marissa Dolorfino , Spent 1 term in lab, plans to continue Fall 2021
Maya Nathwani , Spent 1 term in lab, plans to continue Fall 2021
Hannah Willit , Oncology Crew
Shahriar Tafti , Oncology Crew
Shoaib Siddiqui , Oncology Crew
